Unfortunate comments

An Unfortunate Blow

PLIVA v. Mensing: generic consumers' unfortunate hand.

INTRODUCTION ................................................................................................ 210 I. DRUG APPROVAL PROCESS .......................................................................... 213 A. BRAND-NAME DRUG APPROVAL AND LABELING PROCESS ..................... 213 1. PRE-APPROVAL ...................................................................................... 2...

[Asthma and smoking: an unfortunate combination].

Asthma is an inflammatory disease of the airways in which a key role is played by certain cells and mediators (T-helper 2 cells, mast cells, eosinophils, interleukin 4 and 5). In certain disorders such as irritant-induced asthma, reactive airways dysfunction syndrome, and asthma due to toluene diisocyanate, inflammation is mediated predominantly by T-helper 1 cells, macrophages and neutrophils....

IRIS: the unfortunate rainbow of HIV.

In this issue of Blood, Mahnke and colleagues identify polyfunctional CD4(+) T-cell responses directed against specific opportunistic pathogens in HIV-infected patients who develop immune reconstitution inflammatory syndrome (IRIS) after initiation of antiretroviral therapy (ART). This work provides a mechanistic advance to our understanding of IRIS pathogenesis.

Asthma and Smoking: An Unfortunate Combination

Asthma is a chronic disease of the airways characterized by a disproportionate inflammatory response to specific or nonspecific stimuli.1 Some of the agents that provoke this response are known while others are not. After repeated exposure, these agents eventually trigger sustained inflammation that gets progressively worse, producing secondary alterations in the physiology of the bronchial res...